Skin follows a biological timeline, by deacdes of life. During your 20's and 30's, the first wrinkles start to appear and skin becomes less resistant as elasticity declines and gravity begins to take hold. In your 40's and 50's, repetitive movements form the first permanent wrinkles as genetics, gravity and a decrease in collagen and elastin cause skin and muscle to sag. I have used so many products over my lifetime including Neutrogena, Oil of Olay, Chanel, Clinique, Garnier and Arbonne. The two products that work the best were Arbonne's NutriMinC RE9 and Oil of Olay Total Effects.