By Shane Shirley-Smith
"In conclusion, the findings of this study indicate that Splenda suppresses beneficial bacteria and directly affects the expression of the transporter P-gp and cytochrome P-450 isozymes that are known to interfere with the bioavailability of drugs and nutrients. Furthermore, these effects occur at Splenda doses that contain sucralose levels that are approved by the FDA for use in the food supply."
Cited - "Splenda Alters Gut Microflora and Increases Intestinal P-Glycoprotein and Cytochrome P-450 in Male Rats"
Effects Of Splenda In Male Rats
Mohamed B. Abou-Donia 1, Eman M. El-Masry 1, Ali A. Abdel-Rahman 1, Roger E. McLendon2, and Susan S. Schiffman 3
1 Departments of Pharmacology and Cancer Biology, 2 Pathology, and 3 Psychiatry,
Duke University Medical Center, Durham, North Carolina, USA
Okay so this is a study based on rats (click HERE for the link) and we know humans are different from rats. But what if this happens to you if you ingest Splenda? Drugs and nutrients you need for a healthy life, or to save your life, might not be absorbed properly. This could leave you open to illness. Your gut plays a huge role in fighting disease. In order for it to function properly, a proper bacterial balance needs to be maintained. If Splenda is messing with that balance, that leaves your body vulnerable to disease.
"In conclusion, the findings of this study indicate that Splenda suppresses beneficial bacteria and directly affects the expression of the transporter P-gp and cytochrome P-450 isozymes that are known to interfere with the bioavailability of drugs and nutrients. Furthermore, these effects occur at Splenda doses that contain sucralose levels that are approved by the FDA for use in the food supply."
Cited - "Splenda Alters Gut Microflora and Increases Intestinal P-Glycoprotein and Cytochrome P-450 in Male Rats"
Effects Of Splenda In Male Rats
Mohamed B. Abou-Donia 1, Eman M. El-Masry 1, Ali A. Abdel-Rahman 1, Roger E. McLendon2, and Susan S. Schiffman 3
1 Departments of Pharmacology and Cancer Biology, 2 Pathology, and 3 Psychiatry,
Duke University Medical Center, Durham, North Carolina, USA
Okay so this is a study based on rats (click HERE for the link) and we know humans are different from rats. But what if this happens to you if you ingest Splenda? Drugs and nutrients you need for a healthy life, or to save your life, might not be absorbed properly. This could leave you open to illness. Your gut plays a huge role in fighting disease. In order for it to function properly, a proper bacterial balance needs to be maintained. If Splenda is messing with that balance, that leaves your body vulnerable to disease.
To my knowledge, there have been no long term tests done on humans and the effects of Splenda. Splenda is the trademarked name for sucralose, an artificial chlorinated sweetener that is formed when the hydroxyl groups in a sugar molecule are replaced with chlorine molecules. Initially Splenda was marketed by J&J as a natural sweetener. This did not sit well with the sugar industry or many of Americans who understood that they were being marketed to as though they were idiots. J&J was sued by the Sugar Association for false advertising. Apparently in November of last year, the Sugar Association and McNeil Nutritionals (a division of Johnson & Johnson) jointly declared they reached a settlement. Neither side is allowed to discuss the outcome. Any info on this would be appreciated.
So be clear that it is Sucrose that is naturally produced from sugar beets or sugar cane but there is nothing natural or organic about J&J's Trademarked Splenda, which remember is just sucralose. Sucralose is the chemical compound made by the addition of chlorine atoms to sucrose molecules through a chemical reaction involving a number of chemicals. Sucralose is not natural.
Tate & Lyle, manufacturer of Splenda®, along with its US based co-developer Johnson & Johnson have bought up potentially negative domain names by the hundreds. Names like: splendakills.com, victimsofsplenda.com, splendatoxicity.com are no longer available but we consumers are smarter than T&L and J&J realize...we have Google.
There is so much anecdotal and scientific information online that it becomes easy enough to decide for yourself how much if any Splenda you will ingest. Please be aware that it is in 3500 products including drugs. Stay informed and decide how you want to live your life and whether or not you are willing to take the risk. There really aren't any long term human studies (unbelievable the FDA approved this stuff without further testing) and the rat study really isn't sounding so good. Sadly I stay away from this artificial sweetener too and stick with the purest form of the Stevia plant which you can cook and freeze with.
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